Search results for " bioimaging"

showing 5 items of 5 documents

A Curcumin-BODIPY Dyad and Its Silica Hybrid as NIR Bioimaging Probes

2022

In this paper we describe the synthesis of a novel bichromophoric system in which an efficient photoinduced intercomponent energy transfer process is active. The dyad consists of one subunit of curcumin and one of BODIPY and is able to emit in the far-red region, offering a large Stokes shift, capable of limiting light scattering processes for applications in microscopy. The system has been encapsulated in MCM-41 nanoparticles with dimensions between 50 and 80 nm. Both the molecular dyad and individual subunits were tested with different cell lines to study their effective applicability in bioimaging. MCM-41 nanoparticles showed no reduction in cell viability, indicating their biocompatibil…

Boron CompoundsNIR probeOrganic Chemistryluminescence curcumin BODIPY NIR probes bioimaging bichromophoric dyadGeneral MedicineSettore CHIM/06 - Chimica OrganicaSilicon DioxideCatalysisComputer Science ApplicationsInorganic ChemistryBODIPYNIR probesluminescencebichromophoric dyadSettore BIO/14 - FarmacologiaNanoparticlescurcuminluminescence; curcumin; BODIPY; NIR probes; bioimaging; bichromophoric dyadPhysical and Theoretical ChemistrybioimagingMolecular BiologySpectroscopy
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Idrogel fluorescenti per applicazioni biomediche

2019

Lo studio di idrogel supramolecolari da utilizzare in ambito biomedico è in continua espansione. Questo è dovuto al fatto che, così come gli idrogel polimerici, mostrano eccellenti proprietà meccaniche, ma possono anche essere sottoposti reversibilmente a rigonfiamento o a transizioni gel-sol in risposta a stimoli esterni (temperatura, pH, enzimi, agenti redox).1Ad esempio, la buona risposta degli idrogel supramolecolari agli stimoli fisiologici, insieme alla loro elevata biodegradabilità e biocompatibilità, ne ha permesso l’utilizzo per la diagnosi tumorale. Solitamente, questi materiali sono facilmente assimilati dalle cellule e hanno la funzione di carrier per le molecole attive nel bioi…

Idrogel bioimaging chimica supramolecolareSettore CHIM/06 - Chimica Organica
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Upconversion Nanoparticles for Bioimaging and Regenerative Medicine.

2016

Nanomaterials are proving useful for regenerative medicine in combination with stem cell therapy. Nanoparticles can be administrated and targeted to desired tissues or organs and subsequently, be used in non-invasive real-time visualization and tracking of cells by means of different imaging techniques, they can act as therapeutic agent nanocarriers, and can also serve as scaffolds to guide the growth of new tissue. Nanoparticles can be of different chemical nature, such as gold, iron oxide, cadmium selenide, and carbon, and have the potential to be used in regenerative medicine. However, there are still many issues to be solved, such as toxicity, stability, and resident time. Upconversion …

Materials scienceHistologyMini ReviewBiomedical EngineeringNanoparticleNanotechnologyBioengineering02 engineering and technology010402 general chemistry01 natural sciencesRegenerative medicineNanomaterialschemistry.chemical_compoundUpconversion nanoparticlestransparencyCadmium selenideLow toxicityNIR excitationnon-toxic nanoparticlescell behavior regulationfungifood and beveragesBioengineering and Biotechnology021001 nanoscience & nanotechnologymulti-wavelength/multimodal bioimagingPhoton upconversion0104 chemical scienceschemistryupconverted (UV–VIS–NIR) emissionNanocarriers0210 nano-technologyBiotechnologyFrontiers in bioengineering and biotechnology
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Rapid and eco-friendly synthesis of graphene oxide-silica nanohybrids

2014

The increasing interest in Graphene oxide (GO) is due to many issues: the presence of both sp2-conjugated atoms and oxygen-containing functional groups provides a strong hydrophilicity and the possibility to further functionalize it with other molecules (i.e. π-π interactions covalent attachment etc.) [1]. Furthermore since the GO is biocompatible and noncytotoxic many studies have been recently focused on the development of GO-based nanodevices for bioimaging DNA detection drug delivery. Due to their low cytotoxicity and large internal surface area silica nanoparticles have been taken into account as promising material for biolabeling and drug loading/delivery. Particular consideration has recently been demonstrated for GO-silica composites because of the potentialities for electrical applications their chemical inertia and stability toward ions exposure. The possibility to combine the extraordinary properties of GO and silica offers several advantages for the realization of nanoprobes for biological applications and of biosensor [12]. The strategy for the fabrication of GO-nanosilica nanohybrids can be schematized as follows: (i) synthesis of GO by oxidizing graphite powder with the method described by Marcano et al. [3] (ii) Preparation of oxygen-loaded silica nanoparticles by thermal treatments in controlled atmosphere in order to induce high NIR emission at 1272 nm from high purity silica nanoparticles. (iii) preparation of GrO-silica nanohybrid films via rapid solvent casting in water. The nanohybrids were tested by XPS FTIR Raman analysis UV photoluminescence analysis TGA Zeta potential measurements electrical tests AFM and SEM. Several nanohybrids were prepared by combining two different typologies of GO and two different samples of silica.
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Fluorescent supramolecular hydrogels for biomedical applications

2019

hydrogels imidazolium salts supramolecular gels bioimaging anticancer activity
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